In recent years, LEDs have been found to be innovative in many fields of biotechnology and medicine, such as LEDs to accelerate DNA replication, to treat patients with neurological diseases such as gradual freezing, high-speed flash LED lights to treat dyslexia, and flashing LED lights at specific frequencies. Helps treat Alzheimer's disease; UV-LED, short-wave ultraviolet light can slow the spread of influenza, UVB LED can treat patients with vitamin D deficiency, blue-violet LED can treat bacterial infection and some skin diseases; infrared LED can be treated by irradiation Brain damage, using LEDs with a wavelength of 635 nm for weight loss treatment...
What breakthroughs have LEDs made in the medical field in the past year?
1.Effectively overcome the sleepiness of the morning
According to foreign media reports, researchers from the Korea Institute of Science and Technology (KAIST) said recently that research has confirmed that blue LED lighting can effectively help people overcome the morning sleepiness.
Hyter-Jeong Suk and Kyungah Choi, professors of KAIST's industrial design department, and their team believe that the effects of morning light with blue illumination on the physiological response are time-dependent, and the melatonin levels are alert to warm white light. The subjective feelings of sexuality, mood and visual comfort have a positive impact.
2.Or can achieve painless cardiac resuscitation treatment
Researchers at the University of Leiden Medical Center in the Netherlands have suggested that LEDs help to adjust for arrhythmias.
The team used a bioelectronic defibrillator with LEDs to reset the irregular heartbeat. They developed a system that monitors the rapid arrhythmia in the rat's atrium and sends signals to LED devices implanted near the heart.
Danil Pijnappels, a principal investigator at the Department of Cardiology at Leiden University, said that the flash from the LEDs can cause the heart to generate current and stop the arrhythmia. This is achieved by using gene therapy to introduce specific light-sensitive proteins into the heart, meaning immediate and automatic recovery of the heart's normal rhythm.
Source: Science Translational Medicine
3.It can treat urinary urgency and frequent urination
Chinese and American researchers have restored normal bladder function in rats with frequent urination and urgency by implanting a light stimulation device in rats. This study demonstrates a new system of clinical treatment that is expected to expand into the field of cardiac assist and weight management in the future.
The joint team of Northwestern University, the University of Washington, the Massachusetts Institute of Technology, and the Beijing University of Aeronautics and Astronautics has been able to respond to the stimulation of light by editing genes in cells. In this case, the edited bladder nerve cells inhibit nerve activity under illumination.
To this end, researchers have implanted an LED light device in the abdominal cavity of a rat with a human-induced drug, which is connected to a highly sensitive sensor. The sensor is made of a flexible material that monitors the data around the bladder in real time and wirelessly transmits it to an external recorder.
Once the recorder detects an abnormal bladder signal, such as unnecessarily emptying the bladder, it sends a wireless signal to the LED light in the rat's abdomen to turn on the light. Bladder nerve cells that have been genetically edited beforehand will inhibit the corresponding urination activity under illumination.
4.Help diagnose and treat cancer
The Korea Electronics Technology Research Institute (KERI) said that South Korean scientists have developed a minimally invasive technique that targets tumor cells and uses light-emitting diodes (LEDs) and laparoscopes to diagnose and treat cancer.
Source | KERI
PDT is a technique that uses photosensitizers to "activate" certain types of light to help promote treatment. This technique is more effective because light is only directed at cancer cells rather than normal cells.
Officials at the Korea Electronics Technology Research Institute (KERI) said that KERI's technology uses LED light to detect cancer cells and also uses PDT lasers based on laparoscopic techniques to treat cancer.
Waseda University in Japan also uses LEDs to treat cancer. It is reported that the research team of the school has developed an LED implantable device, which consists of LED chips and bioadhesive nanosheets to successfully shrink tumors in mice through phototherapy.
The implantable device uses metronome photodynamic therapy for the inner surface of animal tissue and releases low intensity radiation to treat targeted lesions for therapeutic purposes. The therapy is a long-term treatment that uses low-dose special drugs and special lighting to kill cancer cells. By using metrological photodynamic therapy directly at the targeted lesion. Can reduce the impact on healthy areas.
5.Fit the skin to show the pulse, ECG
The ultra-thin flexible display developed by researchers at the University of Tokyo can be used to match the skin and display information such as pulse and electrocardiogram.
A breathable micro-mesh electrode with stretchable Micro LED lights and lines creates a slim, flexible display that is only 1mm, making it more fully fit to the skin. In addition to detecting pulse rate through it, you can also connect your smartphone and send important information directly to the cloud system for storage.
This technology is valuable in connecting patients and medical institutions to each other and anywhere, while helping patients to show their vital conditions, while notifying patients and medical institutions through connection devices to assist patients who need nursing at home. .
6.Promote hair growth
The Korea Institute of Science and Technology (KAIST) has developed a Micro LED wearable device that uses vertical Micro LEDs to successfully help mice re-grow their hair.
The device was tested on a back of a mouse that shaved hair using a flexible array of 900 vertical Micro LEDs. After 20 consecutive days of treatment, the hair growth of the mice was significantly faster than that of the untreated mice. Moreover, after treatment, the newly grown hair of the mouse is longer and the hair area is wider.
According to KAIST, Micro LEDs do not heat up to the detriment of the human body, and consume less than one thousandth per unit area compared to conventional phototherapy lasers.
7.Detecting blood oxygen
Engineers at the University of California have developed a flexible OLED sensor to detect blood oxygen in skin, tissues and organs. The surface of the device is an organic photodetector, and the bottom is a red OLED and an infrared OLED. The organic electronic components of the product are printed on flexible plastics and are plasticized according to the contour of the body. The sensor detection range is in the form of a grid. It can detect the blood oxygen level of nine nodes in the grid and can be placed on the skin. any position.
By extensively tracking blood oxygen, the OLED sensor can help monitor wound healing. Suitable diseases include diabetes, respiratory diseases, and the like.